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Vitamin D supplementation may lower blood pressure in obese older adults
Vitamin D supplementation may lower blood pressure in obese older adults, but taking a higher daily dose of vitamin D than recommended by the Institute of Medicines (IOM) does not provide additional health benefits, according to a new study published in the Journal of the Endocrine Society.
The IOM recommends taking 600 international units (IU) of vitamin D per day.
Vitamin D deficiency is a common problem worldwide and has been linked to the development of cardiovascular, immunologic, infectious diseases and cancer. Studies have linked vitamin D deficiency to an increased risk of hypertension, but evidence of a beneficial effect of vitamin D supplementation on blood pressure has so far been inconclusive.
In this study, all participants received 4 calcium citrate tablets (250 mg) and 125 IU of vitamin D3/tablet for a total of 1000 mg of elemental calcium and 500 IU of vitamin D3 per day. In addition, once a week, each participant received 2 identically shaped, colored, sized, smelled, and tasted tablets containing either placebo (low-dose group) or 10,000 IU/tab vitamin D3 (high-dose group).
Older adults (≥65 years of age), overweight (body mass index [BMI] >25), ambulatory, and with serum 25(OH)D levels of 10 to 30 ng/mL at the time of screening were invited to participate in the study.
According to the results of this study, vitamin D supplementation may reduce blood pressure in certain subgroups such as the elderly, obese, and possibly people with low vitamin D levels. High doses of vitamin D compared to the IOM recommended daily dose did not provide additional health benefits.
This was stated by Ghada El-Hajj Fuleihan, an internist at the American University Medical Center in Beirut, Lebanon
Researchers examined data from 221 obese older adults who took vitamin D supplements of 600 IU/day or 3,750 IU/day for a year and found that supplementation reduced blood pressure in these patients.
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