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A health-related quality of life score is reduced in menopausal women with HPV infection
Women with human papillomavirus (HPV) presence at menopause have experienced lower health-related quality of life compared with their age-matched counterparts, researchers report.
“Menopause significantly affects the social, emotional, and physical lives of millions of women worldwide and has a measurable impact on the ability to work. It is also a risk factor for persistent active HPV infection,” write Javier Calvo-Torres, MD, medical resident at the Institute of Women’s Health at the San Carlos Hospital of the University of Madrid, and colleagues in the journal Menopause.
“Although some authors believe that quality of life in menopause depends on several factors, the role of HPV in women in the period immediately before or after menopause and its comparison with the condition much before menopause have not yet been described.”
Calvo-Torres and colleagues conducted a cross-sectional nationwide multicenter study involving 1,016 women with a past or current diagnosis of HPV infection from 17 regions of Spain. All women completed the HPV Quality of Life Questionnaire (HPV-QoL), and the researchers compared demographics, clinical characteristics, and HPV-QoL questionnaire scores with general well-being, sexual performance, health, and infection status in relation to reproductive status. In addition, the researchers tested the correlations with scores on a 12-question general health questionnaire, the Female Sexual Function Index, and the Hospital Anxiety and Depression Scale.
Menopausal assessments were compared between those with and without HPV. Assessments of general health, psychological well-being, and satisfaction with sexual life were lower in menopausal women with HPV.
“This difference in quality of life is significant and is driven by lower scores in the domains of sexual satisfaction, general well-being, psychological well-being, and infection,” the researchers wrote.
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